Nonprofits in South Carolina
The IRS recognises 32,430 tax-exempt organizations with a South Carolina address, rank 22 of 51. 1,726 of them have a Form 990 on record.
American Factbook Research
At a glance
- 32,430
- Organizations recognised
- Registration, not activity.
- 28,544
- Recognised under 501(c)(3)
- The charitable subsection.
- 1,726
- With a Form 990 on record
- The only organizations with financial figures here.
- 591.9
- Per 100,000 residents
- Census resident population as the denominator.
- $40,653,931,636
- Revenue reported
- Summed across filings, each for a different year.
- 1.7%
- Share of all US organizations
- Of 1,964,958 recognised nationally.
Taken from the IRS on September 19, 2026. Address of record, which is not necessarily where an organization operates.
Largest by revenue
2 more columns on a wider screen
| Rank | Organization | Revenue |
|---|---|---|
| 1 | Advanced Technology International | $4,870,021,886 |
| 2 | Prisma Health - Upstate | $3,605,252,123 |
| 3 | Prisma Health-Midlands | $2,076,553,749 |
| 4 | Lexington Health Inc | $1,768,647,290 |
| 5 | Central Electric Power Cooperative Inc | $1,607,586,867 |
| 6 | McLeod Regional Medical Center of the Pee Dee Inc | $1,494,230,490 |
| 7 | Prisma Health-University Medical Group | $925,799,575 |
| 8 | Anmed Health | $854,590,129 |
| 9 | ST Francis Hospital Inc | $850,947,341 |
| 10 | Bon Secours-ST Francis Xavier Hospital Inc | $620,583,353 |
| 11 | Berkeley Electric Cooperative Inc | $594,885,803 |
| 12 | The Blackbaud Giving Fund | $561,434,919 |
| 13 | Roper Hospital Inc | $539,462,922 |
| 14 | Apella Health Management Inc | $524,676,090 |
| 15 | McLeod Loris Seacoast Hospital | $466,863,080 |
The fifteen largest with a filing on record. Organizations without one are counted above but have no figures to rank.
Largest by assets
2 more columns on a wider screen
| Rank | Organization | Assets |
|---|---|---|
| 1 | Prisma Health | $4,640,386,339 |
| 2 | McLeod Regional Medical Center of the Pee Dee Inc | $3,027,944,631 |
| 3 | Roper ST Francis Healthcare | $2,440,152,218 |
| 4 | Lexington Health Inc | $2,302,885,018 |
| 5 | Advanced Technology International | $2,188,924,968 |
| 6 | Anmed Health | $1,541,841,366 |
| 7 | Prisma Health - Upstate | $1,410,597,184 |
| 8 | Prisma Health-Midlands | $1,056,008,104 |
| 9 | The Medical University of South Carolina Foundation | $944,238,249 |
| 10 | Conway Hospital Inc | $864,734,072 |
Book value at the end of the year, which is what all three forms report.
Highest reported compensation
2 more columns on a wider screen
| Rank | Organization | Reported compensation |
|---|---|---|
| 1 | Lexington Health Inc | $4,261,823 |
| 2 | Greenville Health Corporation | $3,374,451 |
| 3 | Prisma Health | $3,374,451 |
| 4 | Prisma Health - Upstate | $3,374,451 |
| 5 | Prisma Health Medical Group-Midlands | $3,374,451 |
| 6 | Prisma Health-Midlands | $3,374,451 |
| 7 | Prisma Health-University Medical Group | $3,374,451 |
| 8 | Apella Health Management Inc | $2,734,045 |
| 9 | Bon Secours-ST Francis Xavier Hospital Inc | $2,539,165 |
| 10 | Roper Hospital Inc | $2,539,165 |
The largest amount an organization here reported paying one person, as reported.
What they do
| Category | Organizations |
|---|---|
| Education | 301 |
| Human Services | 172 |
| Philanthropy, Voluntarism and Grantmaking Foundations | 158 |
| Health Care | 132 |
| Community Improvement and Capacity Building | 78 |
| Arts, Culture and Humanities | 62 |
| Housing and Shelter | 55 |
| Religion-Related | 52 |
| Animal-Related | 42 |
| Recreation and Sports | 42 |
Organizations the IRS never classified do not appear here. A code is assigned at registration and rarely updated, so it describes what an organization said it would do.
Nearest by count
| Rank | State | Organizations |
|---|---|---|
| 21 | Colorado | 36,344 |
| 23 | Arizona | 31,480 |
South Carolina elsewhere on the Factbook
- Reported crimeCrime and justice
Offenses reported to police by type, the trend, and the reporting coverage.
- Cities by violent crime rateCrime and justice
What each agency serving 25,000 or more reported, ranked. Agency populations overlap, so these do not add up to the state.
- Prison populationCrime and justice
People held under the state’s correctional authority, and the imprisonment rate. A different publisher counting a different thing.
- Arrests by race, sex and ageCrime and justice
Arrests as the FBI’s participating agencies reported them, with what the figures can and cannot support at the top.
- Hate crimeCrime and justice
Incidents reported to the FBI by bias motivation, as counts — the collection publishes no participation share, so there is no rate to compare states on.
- Federal obligationsFederal spending
What federal agencies obligated against a place of performance in the state, per resident and by agency.
- Payments to doctorsHealth
What drug and device companies reported paying doctors with a practice address in the state, and the largest recipients.
- Farm program paymentsFarm subsidies
What the Farm Service Agency paid through the state’s county offices, by program and by recipient. The offices that administered the payments, not a count of farms: a recipient addressed elsewhere is counted where they were paid.
- The South Carolina Factbook entryAcross the Factbook
Every measure the Factbook publishes for this state in one place, each with where it ranks among the others and the record it came from.
The immigration hub has no page for this state: EOIR runs no immigration court here, and CBP publishes by sector and field office, which are its own areas of responsibility rather than a geography. Immigration and the border.
Compared with Arizona.
Full rankings: largest by revenue, largest by assets, and largest grantmakers, and highest reported officer compensation. All organizations: nonprofits.
What this page cannot show
- The state is the organization’s address of record with the IRS. A national charity registered here operates elsewhere too.
- Churches need not apply for recognition, so they are under-represented, and the ones here are those that chose to apply.
- Financial figures exist only for organizations with a Form 990 on record, and each describes whichever year that organization last reported.
Full method at methodology.
Sources
- Exempt Organizations Business Master File — Internal Revenue Service · Public domain — U.S. Government work · retrieved September 21, 2026
- Form 990 series e-file data · retrieved September 19, 2026
Data retrieved